- Digitalis inactivates the Na-K-ATPase pump to increase intracellular calcium and extracellular potassium, causing + inoptropy, hence usage in CHF patients
- Dig also increases vagal tone and decreases conduction through the AV node, hence usage in atrial fibrillation. In toxic doses, this is what leads to bradydysrhythmias
Toxicity can either be Acute or Chronic:
Ever notice calcium deposition on an xray and wondered what it meant? Ever read a radiology report that indicated chondrocalcinosis? Check out below for a few pearls related to chondrocalcinosis & pseudogout.
Last week we wrote about how to approach hyponatremia, the differential and signs and symptoms to watch out for. The post this week reviews the treatment of hyponatremia including the dreaded osmotic demyelination syndrome. Read on for more!
Interesting case of a cyanotic patient lately? Looking for good questions to pimp medical students or residents with (had an attending in residency who always loved to ask about way he only recommended pyridium for use for a couple of days for UTI symptoms)? Studying for boards? Below are some teaching points on methemoglobinemia.