Week in Review: Feb 5th - 10th
Most common cause = RSV
Typically age < 2 years
Diagnosis is clinical, due not need CXR
WARM Score to assess if albuterol indicated
Presentation is Late teen to 20s, F>M with AMS, bizarre behavior or weird movements
Diagnosis = CSF anti-NMDA antibody testing (100% sens CSF, 85% sens serum)
Treatment = supportive 75% improve without any intervention
Review of study studies looking at wheter or not it works for ACE-i induced.
Bottomline - limited benefit based on poor data, questionable decrease in length of stay. No RCT data.
Saeb A et al. Using fresh frozen plasma for acute airway angioedema to prevent intubation in the emergency department: A retrospective cohort study. Emergency Medicine International 2016;
Riha MH et al. Novel therapies for angiotensin-converting enzyme inhibitor-induced angioedema: A systematic review of current evidence. Journal of Emergency Medicine 2017; 54 (5): 662-679.
Best used in patients with hypoxic respiratory failure
Should not be used in patietns with hypercapneic respiratory failure (COPD)
Titrate FiO2 from 0.21 to 1.00. Use a rate of 2-8 L/min in Peds and 16-60 L/min in Adults
So you diagnosised compartment syndrome, nice job. Now which compartment is most likely to be effected?