Back to Basics: Acute Renal Failure
ARF can lead to: volume overload, hypertension, pulmonary edema, neurologic symptoms, anemia, increased susceptibility to infection, etc.
- Prerenal failure is caused by condition that decrease renal perfusion, it is the most common cause of community acquired actue renal failure
Postrenal failure occurs primarily in elderly men with prostate obstruction
Common nephrotoxic drugs causing intrinsic tubular disease : aminoglycosides, cisplatin, amphotericin B
Common drugs associated with acute interstitial nephritis : NSAIDs, antibiotics, diuretics, phenytoin, allopurinol
Common dialyzable drugs : lithium, aspirin, methanol, ethylene glycol, theophylline
Tintinalli, JE. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. 8th ed. New York, NY: McGraw-Hill Education LLC, 2016.