An intubated 32 year old female is brought to the ED in cardiac arrest. Family was suspecting that this was an overdose.\ given a recent hospitalization for acetaminophen overdose. EMS reports that on arrival the patient had a bluish discoloration to the skin, and she is now extrememly pale with the appearance of a cadaver. What could have caused this clinical picture? Read on for a discussion of a very rare but extremely deadly poisoning...
A 55 year old patient presents via EMS reporting a large ingestion of his home oral phenytoin. As you go to evaluate the patient, you consider the clinical manifestations and possible complications of a phenytoin overdose. Is this a serious overdose? Is there a high potential for decompensation and the dreaded tox "seizure/coma/death" triad? Are there effective antidotes? Good thing you read this article!
Admittedly not so much a “basic” concept, but this does bring me back to textbooks and medical school. Having seen this recently in a real patient, thought it was useful to review. Highlights the importance of a good medication reconciliation!
MAOI + tyramine tyramine reaction hypertensive urgency/emergency
Tox in the News lecture with Matt Salzman, MD
New reports of ingestion of chloroquine for prophylaxis of COVID-19, chloroquine which was meant to clean fish tanks, resulting in critical illness and death … do not do this ...